This workshop panel and moderated discussion will focus on distinct populations, not typically covered in the PrEP conversations or mentioned in PrEP guidelines. Join our panel discussion for a richer story that is emerging from distinct populations around HIV prevention, including PrEP: API transwomen, Native Americans, people who access abortions or family planning, people who desire conception/safer conception, people who are substance involved, API MSM, and people who exchange sex for survival. From a strengths based perspective, invited panel participants will present background information (5-6 minutes each) on facilitators and barriers for reaching distinct populations, i.e. those currently left out of the mainstream PrEP dialogue, who may benefit from an expanded HIV prevention toolkit. The use of storytelling as a method for overcoming stigma and including people from distinct backgrounds will be described. The moderated panel discussion will include the lived experience of audience members as participants, providing a highly interactive and engaging format. Resources will be shared. The panel discussion will be summarized with best practices for moving forward with an inclusive PrEP implementation agenda.